Supply chain attacks represent one of the most pervasive threats in modern cybersecurity, with the potential to compromise thousands of systems simultaneously. This talk presents a detailed technical analysis of a supply chain compromise campaign, which successfully compromised multiple NPM and PyPI packages within a 10-day period, affecting packages with over 30 million weekly downloads. We’ll highlight how earlier variants targeted smaller, lesser-known assets before pivoting to high-visibility projects, and how technical similarities across samples linked this operation to previous malware families.