Ransomware attacks have become a pervasive threat to global organizations, causing substantial financial losses over the past decade. The increase in successful ransomware attacks is driven by multiple factors and the issue has proven challenging to track by the industry and researchers. A major obstacle to accurately quantifying the impact lies in the fragmented nature of available data and the lack of centralized oversight. This call to action takes a multidisciplinary perspective to analyzing cybersecurity risk and ransomware threats across various industries and provides insights into the vulnerability profiles of sectors targeted by ransomware operators. Furthermore, this study examines the challenges associated with mitigating these risks, including the technological evolution of attack variants, sophistication of tooling in the AI/ML era, and the importance of readiness.