AI, machine learning and automation are not new to cyber security. In fact, they form part of most core processing engines that make up the entire cybersecurity technology capability of an organization. With the ever-increasing sophistication of threat actors and attack vectors, there is a need to explore advanced defence mechanisms. In this presentation we will consider the current cyber defence value chain, establish its limitations and introduce an advanced ML-driven cyber defence value chain model as an approach to keep up with the pace of sophistication in the threat landscape.