What does it take to set up a Cyber Defence Center? How do you organise your defence in a context of an ever-evolving threat landscape and the increasing complexity of your infrastructure? The presentation will share practical lessons learnt from setting up one of the most sophisticated and respected CERTs in Europe. What are the main building blocks of a successful CDC, which are the best sources of information, how to attract and retain expertise? What are the quick starts and low hanging fruits? How to be successful in the long run?