SARS, H1N1, MRSA, Zika, Ebola. The human body is terrifyingly vulnerable. With the rise of novel gene-editing techniques and our increasing knowledge of genomics, we are forced to confront the idea of a microscopic enemy. This talk will explore the not-so-theoretical aftermath of an unchecked pandemic of unknown origin, the monsters we created in our own medical hubris, and the ever-present threat of bioterrorism. The unpredictability of such weapons, and our inability to create safety brakes for the ones we do create will also be discussed.