The design and implementation of network and system segmentation in medium to large environments can be challenging as there appears to be no common approach for implementation and communication of segmentation to technical and business units. This talk will describe the challenges of such implementation and summarize the potential solutions for physical and logical alignment, and its socialization. The material presented will be based on recent and ongoing experience with designing, implementing, and communicating network and system segmentation via numerous hands-on table top exercises, and analysis of numerous literature sources.