In the past few decades, public opinion of chemistry has changed from a benign and fairly wholesome activity to an inherently suspicious and dangerous one. While chemical experimentation should be approached with a degree of caution, scientific history is filled with important discoveries made by at-home tinkerers. This talk will explain how to create a functioning lab capable of exploring current research topics such as nanotechnology on a home tinkerer's budget, and how to use that equipment to make materials suitable for use in art and general hacking projects.