It is well known there is a race going on in the "Big Data" arena (take a drink for even thinking about the "Internet of Things"). One of the stronger competitors in the "Big Data" market is Real-Time, In-Memory Platforms. An interesting thing about this platform and, the one we will talk about specifically, is that it blends everything to increase performance. The database tables, webserver engine, webserver code, authorization, analytics engine, libraries, etc. are all optimized to, if possible, never touch the disk. Surprisingly, this causes a perspective shift for the web and database application threat landscape and how security professionals should address it. Ezequiel Gutesman is Director of Research at Onapsis. He has led security research projects for the last 10 years giving talks and presentations in international security conferences such as Black Hat, Hack.Lu and Ekoparty. Ezequiel is responsible for Onapsis innovation in cutting-edge ERP security assessment techniques and defensive technologies.